The different chapters of this book detail the role of different cytokines and chemokines in specific autoimmune disorders in this chapter i highlight the contributions of individual cytokines and chemokines to multiple autoimmune diseases as discussed in detail throughout the book1 14 the reader is referred to specific chapters for details. Cytokines a varied group of signaling chemicals in the body have been described as the software that runs the immune system but when that software malfunctions dysregulation of the immune . Cytokines including proinflammatory cytokines and anti inflammatory cytokines are important players in the pathogenesis of these diseases through multiple ways such as regulating inflammation and angiogenesis in this special issue we present original research articles as well as review papers on the role of cytokines in autoimmune diseases. Leading experts in the field of cytokine research present their most up to date findings and unique perspectives on the role of cytokines in autoimmune diseases in a special issue of journal of . Cytokines and autoimmune disease 283 inherited abnormalities in cytokine production may predispose to the development of autoimmune diseases the in vitro il 2 deficiency is accentuated during active phases of the autoim mune process 33 52
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