History of vaccine development you can read more about the state of the worlds vaccines and immunization in this executive summary from who it was one of the scourges of early human history a worldwide case detection and vaccination programme against smallpox gathered pace and in 1979 the world health assembly officially declared . Vaccine development is a long complex process often lasting 10 15 years and involving a combination of public and private involvement the current system for developing testing and regulating vaccines developed during the 20 th century as the groups involved standardized their procedures and regulations government oversight. Plague vaccine was also invented in the late 19th century between 1890 and 1950 bacterial vaccine development proliferated including the bacillis calmette guerin bcg vaccination which is still in use today in 1923 alexander glenny perfected a method to inactivate tetanus toxin with formaldehyde. The history of vaccines now goes back over 300 years to the work of jenner but the last 50 years have seen an enormous acceleration of the pace of vaccine development and accordingly the impact on infectious diseases
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