Regulatory t cells and clinical application and millions of other books are available for amazon kindle learn more enter your mobile number or email address below and well send you a link to download the free kindle app. Get this from a library regulatory t cells and clinical application shuiping jiang a major process of rediscovery has taken place in the field of cellular immunology over the past 12 years subsets of t lymphocytes exist that are specifically dedicated to regulation or as it should . Regulatory t cells can be best thought of today as teenagers ready to take on all the challenges of complex immune responses in ten years the field will certainly be more mature and manipulation of regulatory t cell function by cellular biotherapy antibodies and small molecules will be routine function of the clinical immunologist. Regulatory t cells tregs are a subgroup of suppressive cd4 t cells that play a vital role in the maintenance of host immune homeostasis treg deficiency can induce severe autoimmune hypersensitivity and auto inflammatory disorders among other diseases. Treg cells for clinical applications can be either enriched or depleted using the clinimacs cell separation system in combination with the clinimacs cd25 reagent infusion of clinical grade enriched regulatory t cells delays experimental xenogeneic graft versus host disease transfusion 542 353 363
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