Immune system disorders occur when the immune response is directed against body tissue is excessive or is lacking allergies involve an immune response to a substance that most peoples bodies perceive as harmless. Infection occurs when a pathogen invades body cells and reproduces infection will usually lead to an immune response if the response is quick and effective the infection will be eliminated or contained so quickly that the disease will not occur sometimes infection leads to disease. The immune response to infection 1 non specific immunity the immune system has evolved to deal with infectious pathogens there are several lines of host defence when evaluating the cause of infection in any patient it is important to exclude non specific immune defects. Immune response to infection when a pathogenic disease causing microorganism invades the body for the first time the clinical observable response may range from nothing at all through various degrees of nonspecific reactions to specific infectious disease . Pro and anti inflammatory response following surgical trauma local inflammatory response in the surgical wound observed in the early postoperative period is associated mainly with the activation of innate immune mechanisms the influx of neutrophils and monocytes into the wound and the production of cytokines and chemokines
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